
Nicotiana setchellii
Image: Sherwin Carlquist (cc-by-nc)
NameNicotiana setchellii
Scientific NameNicotiana setchellii Goodsp.
Common NamesSetchell's Tobacco, Wild Tobacco
Plant FamilySolanaceae
Natural HabitatFound in dry, open areas, often disturbed sites, chaparral, and oak woodlands in California.
Parts Usedleaf,whole_plant
Medicinal Actionsanalgesic,nervine
Traditional UsesTraditionally, various indigenous peoples of California used Nicotiana setchellii for ceremonial and spiritual purposes, often consumed as a stimulant or narcotic. Topically, it was sometimes applied as a poultice for localized pain relief or to treat insect bites. It is important to note its high toxicity and addictive nature, and it is not safely used as a conventional medicinal herb.
Active ConstituentsNicotine, Anabasine, Nornicotine
Preparation Methodspoultice,powder
Contraindications & WarningsHighly toxic and addictive. Not for internal consumption due to severe poisoning risk. Contraindicated in pregnancy, lactation, heart conditions, hypertension, and by individuals sensitive to nicotine. Can cause severe poisoning and should be handled with extreme caution; seek immediate medical attention if ingested.
Cultivation NotesAn annual herb, Nicotiana setchellii thrives in full sun and well-drained soil. It is typically propagated from seed and requires minimal water once established, preferring dry conditions.
Raritycommon
Description
Nicotiana setchellii is an annual herbaceous plant native to California, typically growing up to 1 meter tall. It features sticky, glandular leaves and produces white to yellowish-green, tubular flowers. The image provided shows a microscopic cross-section of its stem tissue, revealing vascular bundles and parenchyma cells.




